Maternal serum of thirty nine ewes were used to study hematological and antibody responses of chicken
injected with antigen protein of specific LDH obtained from sheep with different litter sizes (prolific type). The prolific
type of ewes was determined base on litter size (LS), which were low (1 ≤ LS ≤ 1.5), medium (1.5 < LS ≤ 2.0), and high
(LS > 2.0). There were ten ewes carrying specific LDH protein. The number of animals of low, medium, and high prolifictype
ewes was 3, 5, and 2 heads, respectively. The serum was used to produce antigen and injected to chicken to promote
antibody production of anti LDH. The results of research showed that different prolific-type has no significant (P>0.05)
effects on hematological and antibody titer of chicken. However, hematological status of chicken injected with specific
LDH antigen was significantly (P